Endocrine Abstracts

Introduction: Primary aldosteronism (PA) is frequently recognized as the main cause of secondary hypertension. Its prevalence is on the rise, impacting a range of 1 to 30% among individuals with hypertension.Patients and methods: Retrospective and descriptive study concerning 40 patients with PA, collected in the endocrinology department of the Hedi Chaker University Hospital of Sfax, over the period of 10 years from January 2010 to December 2022.<p ...

Introduction: Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder affecting adrenal steroid synthesis. Its treatment aims to achieve a balance between optimal glucocorticoid replacement and normal androgen levels. The long-term outcomes of this condition are poorly studied. The objective of this study is to evaluate the impact of CAH due to 21-hydroxylase deficiency on final height (FH), bone metabolism, and cardiometabolic risk in a Tunisian cohort.<p ...

Introduction: Distal and symmetrical peripheral polyneuropathy is the most frequent type of diabetic neuropathy. Its painful form (PDN) is the most common cause of non-traumatic neuropathic pain and can place a heavy burden on elderly patients’ lives. Despite the major impact that it can have on the quality of life, PDN is generally underdiagnosed because of a large interindividual variability of symptoms and in the absence of well-established diagnostic criteria.<p c...

Introduction: Mitochondrial diabetes (MD) is characterized by a wide spectrum of phenotypic and genotypic manifestations. Through a cohort study of 40 patients with MD, we attempted to establish a correlation between this diversity of phenotypic expression and the biomolecular substrate of the mitochondrial genome within the Tunisian population.Results: Epidemiologically and anthropometrically, our series aligns with literature data, with an onset age of...

Introduction: Metabolic syndrome (MS) is responsible for the increased cardiovascular risk in type 2 diabetics. There is a scarcity of research on the metabolic syndrome among individuals diagnosed with type 1 diabetes (T1DM). The aim of this study is to describe clinical, biochemical and therapeutic characteristics of T1DM with MS.Materials and Methods: Retrospective study including 36 patients, with T1DM and MS, hospitalized in the department of Endocr...

Background: Low medication adherence is a frequent problem in elderly individuals with chronic diseases such as diabetes. The objective is to assess the level of medication adherence and identify predictive factors for poor adherence among elderly diabetic patients.Methods: We conducted a descriptive, cross-sectional study among diabetic patients aged 65 years and older, who were attending the Endocrinology Department at Hedi Chaker University Hospital i...

Introduction: Diabetic foot wounds (DFW) are one of the most challenging complications of diabetes. DFW is one of the leading causes of foot ulceration and amputation in patients with diabetes mellitus. Then, a multidisciplinary approach is of a great importance in the prevention and management of DFW. Healthcare personnel, particularly nurses, have an important role in this process. The objective of our study was to evaluate nurses ‘knowledge on diabetic foot wounds mana...

Introduction: Diabetic retinopathy (DR) is the most common cause of acquired blindness. Patient information about its course and prognosis is key to insure therapeutic adherence and reduce the risk of blindness. The aim of this study is to assess Tunisian patients’ level of knowledge about DR and to correlate it with DR severity. Methods: We conducted a cross-sectional descriptive and analytical study of diabetic patients with DR followed at outpati...

Introduction: Diabetic foot is a significant public health issue, and its management remains challenging, emphasizing the importance of prevention through the screening of high-risk feet and educating diabetic patients about preventive care.Objectives: To assess, using a questionnaire, the knowledge and practices of diabetic patients regarding diabetic foot care and to determine the level of podiatric risk in our diabetic patients according to the Intern...

Introduction: The diabetic foot represents a major public health problem worldwide, as it exposes patients with diabetes mellitus to a high prevalence of ulceration and amputation, with potential repercussions on patients’ quality of life and even the society through its economic impact. Health care personnel, particularly nurses, play a crucial role in the management and prevention of diabetic foot disease. The aim of our study was to assess nuses’Knowledge levels o...